The following is a summary of “IRF2BP2 Deficiency: An important form of common variable immunodeficiency with inflammation,” published in the March 2025 issue of Journal of Allergy and Clinical Immunology by Udemgba et al. Interferon regulatory factor-2 binding protein-2 (IRF2BP2) regulates immune pathways, angiogenesis, apoptosis, and cell differentiation. Its defects lead to immunodeficiency. Researchers conducted […]
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