Hereditary cancer syndromes account for 6-10% of all colorectal cancer (CRC) cases and 20% of early-onset CRC. Identifying novel pathogenic germline variants can impact genetic testing, counseling, and surveillance. This study aimed to determine the prevalence of germline variants associated with hereditary CRC in the Iranian population.Whole exome sequencing (WES) was conducted on DNA from […]
The post Germline variants in patients from the Iranian hereditary colorectal cancer registry. first appeared on Physician’s Weekly.
