The role of the extracellular matrix (ECM) in guiding cell fate has spurred the development of synthetic, ECM-inspired regenerative biomaterials. We previously described a porous, open-cell foam composed of nanoparticulate mineralized collagen glycosaminoglycan (MC-GAG), capable of inducing in vitro osteogenesis of primary human mesenchymal stem cells (hMSCs) and in vivo skull regeneration without adding growth […]
The post Orai1 is Required for Osteogenic Differentiation on Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials. first appeared on Physician’s Weekly.