Blackandmed

In clear aligner treatment (CAT), closure of the premolar space is achieved by reducing aligner length. Posterior anchorage preparation is effective in preserving molar angulation; however, the resulting distal tipping...

Scoliosis considerably affects adolescents’ physical well-being and quality of life. Current research offers scant data concerning the correlation between abnormal posture, screen time, physical activity, and adolescent scoliosis. This study...

The efficacy and safety of pemigatinib in advanced cholangiocarcinoma (aCCA) were presented in phase I-II trials and retrospective reports, with small sample sizes and variable results.A systematic literature search included...

Hereditary cancer syndromes account for 6-10% of all colorectal cancer (CRC) cases and 20% of early-onset CRC. Identifying novel pathogenic germline variants can impact genetic testing, counseling, and surveillance. This...

Glioblastoma (GBM) is an aggressive Grade IV brain tumor with a poor prognosis. It results from genetic mutations, epigenetic changes, and factors within the tumor microenvironment (TME). Traditional treatments like...

Recently, we found, using a cigarette carcinogen-induced lung cancer model, that soy protein isolate (SPI) was superior to casein in preventing lung cancer. In this study, we have attempted to...

Birth weight (BW) is a key indicator of a newborn’s health, survival, and development. It is associated with the risk of childhood mortality and is also related to health, physical...

Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), has demonstrated promising outcomes in treating HER2-negative early-stage breast cancer with BRCA mutations. However, a comprehensive evaluation of its cost-effectiveness in the...

Endoplasmic reticulum (ER) stress is increasingly recognized as a driver of cancer progression; however, the precise molecular mechanisms by which ER stress facilitates tumor metastasis remain incompletely understood. In this...

Chronic insomnia and obstructive sleep apnea commonly co-occur. Few studies have explored the neurophysiological and neurocognitive characteristics of COMISA, which could help guide improving treatment diagnostic tools and determining novel...